Preheat and Prepare: Begin by preheating your oven to 375°F (190°C).
Create the Creamy Mixture: In a mixing bowl, combine the cream of chicken soup, sour cream, garlic powder, onion powder, paprika, salt, and pepper. Stir until smooth.
Arrange the Chicken: Pat the chicken breasts dry with paper towels.
Add the Cheese and Breadcrumbs: Sprinkle the shredded cheddar cheese evenly over the creamy layer.
Bake to Perfection: Cover the baking dish tightly with aluminum foil and bake for 25 minutes.
Rest and Garnish: Remove the chicken bake from the oven and let it rest for about 5 minutes.